In addition, recent published sequencing studies have identified genetic mutations associated with CD that are located on chromosome 7, such as BRAF (MAPK pathway, located on 7q34), WEE2 (located on 7q34), KMT2E (chromatin remodeling, located on 7q22), HDAC9 (chromatin remodeling, located on 7p21), and DNAH11 (cell function, located on 7p15). This evidence concerns the gene HDAC9 and Cowden disease.