Overall, these studies indicate that substantial differences may exist among the various cell histotypes in terms of receptors and absorption rate of vitamin C. Therefore, future studies aimed at understanding the preferential uptake of vitamin C by cancer cells should not only include analysis of the expression of GLUT1, GLUT3, and SVCT2 transporters but also measurement of vitamin C content inside the cells after treatment. This evidence concerns the gene SLC2A3 and cancer.