Wilms tumor gene (WT-1) peptide-based vaccines (containing HLA-A*2402-restricted, natural, or modified 9-mer WT1 peptide emulsified with montanide ISA51 adjuvant) were generally well-received and achieved specific cytotoxic T-cell reactivity resulting in reduced leukemic burden with markedly decreased MRD markers in the majority (60%) of treated AML patients after consolidation therapy [151]. The gene discussed is WT1; the disease is acute myeloid leukemia.