NPPB and acute coronary syndrome: A few studies noted a relationship between CRP concentration during acute MI and post-infarct HF but were subject to limitations such as heterogenous populations with different types of acute coronary syndromes including STEMI patients and a lack of multiple serial high-sensitivity CRP measurements at various time-points of acute MI, a lack of guideline-based therapies in all patients, no use of primary PCI, no echocardiographic monitoring of LV function and LVR, no measurements of other valuable biomarkers such as BNP and/or a lack of long-term follow-up [18,19,20,39,40,46].