STAT3 and glioblastoma: Numerous researches have stated that Qu enhances the efficiency of glioblastoma therapy by repressing the PI3K-Akt pathway [163], arresting cells at the G2 checkpoint of the cell cycle, and reducing the mitotic index in glioma cells [277], blocking STAT3 [115], and causing apoptosis by reducing the X-linked inhibitor of the apoptosis protein (XIAP) [278] [278].