For example, the RTB101/rapamycin clinical trial described previously (ANZCTR ID: ACTR N12619000372189) targets the mTOR complex, which is not itself associated with PD, but is involved in a signaling pathway that regulates autophagy and has been shown to rescue dopaminergic neuron degeneration in some PD models [72]. Here, MTOR is linked to Parkinson disease.