We found that tumours with G-CSFhigh and CAIX+ phenotypes independently displayed highly significant positive correlations with the presence of intratumoural lymphocytes expressing CD8, PD-1, FOXP3, TIM3, and LAG3, with carcinoma cells expressing PD-L1, and with CD163+ M2 macrophages (Table 2). The gene discussed is LAG3; the disease is neoplasm.