Several of the proteins impacted by myectomy (POSTN, MMP12, CDON, NAMPT, HAMP, LTA4H) were previously reported to be altered in cardiovascular disease, cardiomyopathy, or vascular disease with effects mediated through inflammatory mechanisms [5,6,7,8,9,10,11,12,13]. Here, MMP12 is linked to cardiomyopathy.