Several of the proteins impacted by myectomy (POSTN, MMP12, CDON, NAMPT, HAMP, LTA4H) were previously reported to be altered in cardiovascular disease, cardiomyopathy, or vascular disease with effects mediated through inflammatory mechanisms [5,6,7,8,9,10,11,12,13]. The gene discussed is POSTN; the disease is cardiovascular disorder.