Several of the proteins impacted by myectomy (POSTN, MMP12, CDON, NAMPT, HAMP, LTA4H) were previously reported to be altered in cardiovascular disease, cardiomyopathy, or vascular disease with effects mediated through inflammatory mechanisms [5,6,7,8,9,10,11,12,13]. This evidence concerns the gene CDON and cardiomyopathy.