IL13Rα2 was hypothesized to be a decoy receptor for IL13Rα1 and the type II IL-4R complex [67,68], but updated evidence suggests that IL-13 may signal through IL-13Rα2 to promote pancreatic cancer cell proliferation and invasion [68,69,70]. The gene discussed is IL13RA2; the disease is familial pancreatic carcinoma.