The first group comprises four main type of disorders such as Guillain-Barre Syndrome (GBS), chronic inflammatory demyelinating polyradiculoneuropathy (CIDP), anti-myelin associated glycoprotein (MAG) neuropathy and polyneuropathy, organomegaly, endocrinopathy, m protein and skin changes (POEMS) syndrome. The gene discussed is MAG; the disease is chronic inflammatory demyelinating polyradiculoneuropathy.