Some well-characterized examples include mutations in the genes encoding versican, which provokes erosive vitreoretinopathy and Wagner disease [23]; biglycan, which causes Meester-Loeys syndrome characterized by skeletal anomalies or aortic aneurysm [24]; perlecan, related to the Schwartz-Jampel syndrome characterized by skeletal dysplasia and myotonia [25]; or nyctalopin, involved in a type of night blindness [26]. This evidence concerns the gene BGN and Wagner disease.