Recently, it has been demonstrated that the DNA damage response serine/threonine kinase ATM (mutated in ataxia–telangiectasia) increases FPN expression by enhancing the nuclear translocation of metal-regulatory transcription factor 1 (MTF1) [27], which was previously found to trigger FPN expression [28]. This evidence concerns the gene SLC40A1 and Ataxia-telangiectasia.