RPS6KB1 and cancer: Depending on the type of cancer there are different levels of episodes of ATG genes, markers of high risk of recurrence of colorectal are: ATG16L2, CAPN2 and TP63 upregulation, ATG5 downregulation and other genes associated with autophagy, i.e., SIRT1, RPS6KB1, PEX3, UVRAG and NAF1. Other factors that contribute to the development of gastric cancer are ULK1, BECN1, ATG3 and ATG10 [75,76].