LMTK3 and cancer: Additionally, tumor-suppressive microRNA-34 (miR-34), well-known for the modulation of such target genes as Notch homolog 1 (NOTCH1), C-MYC, lemur tyrosine kinase 3 (LMTK3), and KLF4 [55], consequently can suppress stem-like characteristics in many types of cancer [56,57,58] and is suggested to influence stemness in ChS.