We found that ANXA1 expression was significantly correlated with the area under the curve (AUC) of gemcitabine and doxorubicin in the primary PC cell lines (Figure 7; Spearman’s rank correlate coefficient® = 0.587 (p = 0.03) and r = 0.535 (p = 0.03), respectively) and negatively correlated with the AUC of 5-fluorouracil in the metastatic PC cell lines (Figure 7; r = −0.553 (p = 0.01)). This evidence concerns the gene ANXA1 and pachyonychia congenita.