Stearoyl-CoA desaturase-1 (SCD1), which catalyzed the conversion of stearoyl-CoA and palmitoyl-CoA into the monounsaturated fatty acids oleate and palmitoleate, contributed to β-catenin nuclear localization in MDA-MB-231 breast cancer cells to drive EMT [82]. The gene discussed is SCD; the disease is breast cancer.