This can be seen by the reduced secretion of typical inflammatory cytokines such as IL-6, IL-12, IL-2, IFN-γ, TNF-α, IL-8, GM-CSF, and IL-1β [48,49,50] and the increase in production of IL-4, IL-10, and PGE2 [48], which are commonly considered drivers of a tumor-promoting microenvironment [56,57,58]. The gene discussed is IL10; the disease is neoplasm.