Levels of sCD163 were measured in severe sepsis patients by Feng et al. which showed a peak median of 4190 ng/mL on day 5 of intensive care unit admission, Bleesing et al. showed sCD163 levels in patients diagnosed with autoimmune-associated MAS to be 23,000 ng/mL, and Sadaat and Jang, indicated a level of 6384 ng/mL in a malignancy-related MAS patient [78,91,113]. The gene discussed is CD163; the disease is macrophage activation syndrome.