MTHFR and androgen insensitivity syndrome: Our previous study on children with AIS demonstrated that both carriers of the T allele of 677C>T polymorphism in the MTHFR gene and the T allele itself are associated with an increased risk of AIS in male paediatric patients suffering from stroke (odds ratio (OR) = 3.09, p = 0.023, and OR = 3.09, p = 0.009, respectively) [88].