Compared to our previous study (Gugel et al. 2019 [10]) which investigated the long-term postoperative hearing follow-up in a smaller cohort of young, age-matched NF2 patients, the current study did not confirm the finding of significant reduction of postoperative tumor growth rate or a significant correlation between preoperative tumor volume and postoperative hearing deterioration. This evidence concerns the gene NF2 and neoplasm.