Most importantly, as there is no actual correspondence between the results of immunohistochemistry and FISH [32], these cases with MYC and BCL2 double-expression but lacking D/TH remain within the bounds of DLBCL-NOS but more often belong to the ABC/non-GCB subtype and require further studies to definitively assess their prognostic and/or therapeutic relevance [1,32]. This evidence concerns the gene MYC and diffuse large B-cell lymphoma.