PYY and Cowden disease: Investigation of EEC peptides and appetite-related symptoms in response to a mixed nutrient test meal in active ileal CD patients (n = 12), inactive ileal CD patients (n = 6), active colonic CD patients (n = 5), and controls (n = 13) showed a 2-fold increase in pre- and postprandial total PYY plasma levels in active ileal CD patients compared with controls and active colonic CD patients [117].