Other breast cancer susceptibility genes that have equivalent information include BRCA2 (penetrance to age 70, 45% (95% CI, 31–56%) [27], PALB2 (penetrance to age 70, 44% (95% CI, 37–52%) [28] and BRCA1 (penetrance to age 70, 65% (95% CI, 44–78%) [27]. The gene discussed is BRCA1; the disease is breast cancer.