Even a combined analysis of a serum panel of potential breast cancer markers, consisting of osteopontin, haptoglobin, haptoglobin, CA153, CEA, CA-125, prolactin, CA19-9, α-fetoprotein, leptin and migration inhibitory factor, is unable to predict the presence of early-stage breast cancer [9]. This evidence concerns the gene CEACAM5 and breast carcinoma.