In lung cancer, overexpression of miR-17 and miR-19 affects the expression of HIF1A, PTEN, BCL2L11, CDKNA, and TSP1, enhancing tumor growth by increasing the permeability of blood vessels, inducing hypoxia, increasing proliferation, inhibiting apoptosis, and stimulating tumor cell migration [139,140]. This evidence concerns the gene HIF1A and neoplasm.