Of the five heterozygous variants identified as candidate causes of inherited cardiomyopathy by whole exome sequencing in the proband, Sanger sequencing confirmed the presence of a heterozygous frameshift mutation (NM_000256.3:c.3313_3314insGG; p.Ala1105Glyfs*85) in <i>MYBPC3</i> in the proband and his affected daughters, but not in his unaffected granddaughter. This evidence concerns the gene MYBPC3 and cardiomyopathy.