Inhibition of TRPA1 alone or TRPA1 and TRPV1 simultaneously shows better effects than the inhibition of TRPV1 alone, suggesting that TRPA1 is more sensitive to the oxidative stress induced by PM2.5 than TRPV1, and that TRPA1 might have a more important role in asthma generation [105,106,107,108,109]. Here, TRPV1 is linked to asthma.