BCL2L1 and colorectal cancer: Among the miRNAs able to act against Bcl-xL we cite let-7c/g, which negatively regulates Bcl-xL expression [88]; miR-491 which is able to induce apoptosis by targeting Bcl-xL in different tumor types such as glioblastoma, ovarian and colorectal cancer [89,90,91]; miR-34a that is able to target Bcl-xL [92]; and miR377 that represses Bcl-xL [93].