Experiments in nude mice bearing human cancer xenografts demonstrated that the uptake of [99mTc]Tc-ZHER2:41071 in HER2-expressing SKOV-3 xenografts was significantly (p < 0.0005) higher than in HER2-negative Ramos xenografts 4 h after injection (Figure 8), which confirmed that the tumour accumulation was HER2-specific. The gene discussed is ERBB2; the disease is neoplasm.