SLC2A1 and cancer: In addition to transcriptionally regulating the cell cycle and maintaining genomic stability, FOXM1, upregulated early in HNSCC tumorigenesis, promotes the Warburg effect by transcriptional activation of GLUT1, HK2, and LDHA in multiple cancer cell lines and critically combats oxidative stress by inducing ROS scavenger gene expression [137,138,139,140].