Hight al. reported on the potential of the peptide-based 18F-FB-VAD-fluormethylketone caspase 3 substrate to visualize apoptosis-induction in (V600E)BRAF colon cancer xenografts in mice using a combined BRAF-mutation inhibitor and a dual P13K/mTor inhibitor [55]. This evidence concerns the gene BRAF and colonic neoplasm.