INS and hydrops fetalis: In addition, age (HR: 1.07 (1.03–1.10); p < 0.001), ejection fraction < 40% (HR: 2.60 (1.22–5.51); p = 0.012), HDL-c plasma levels (HR: 1.05 (1.02–1.08); p = 0.001) and treatment with insulin (HR: 3.22 (1.28–8.13); p = 0.013) were associated with an increased risk of developing HF and death in patients with persistent inflammation (Table 4).