CASP3 and breast cancer: Similar in vitro and in vivo experiments, by Li et al., on cell lines and BC patient tissue, regarding the role of exosomal miR375-3p in BC suppression, indicated that miR375-3p–loaded exosomes increased cancer cell apoptosis by increasing caspase 1 and caspase 3 expression while on the other hand inhibited cancer cell proliferation and migration.