The in vivo production of the T cell tumor trafficking chemokine C-X-C motif chemokine ligand 10 (CXCL10) increased in murine lung cancer cells accompanied by retarded tumor growth with anti-PD-L1-IFN-α compared to parental anti-PD-L1 and a non-specific immunocytokine [66]. The gene discussed is CD274; the disease is lung carcinoma.