They are also ligands of histamine H4 and H3 receptors [13,14], inhibitors of IRAK4 (interleukin-1 receptor-associated kinase 4) [15], the vascular endothelial growth factor inhibitor [16], serine/threonine protein kinase inhibitors, candidates for treating drug-resistant tuberculosis [17]. Here, IRAK4 is linked to tuberculosis.