In terms of the expression of TLR-4, at 2 h of infection, a statistically significant overexpression was observed induced by the serotype a (p = 0.0048), b (p = 0.0055) and c (p = 0.0018) compared to the control condition; and likewise at 24 h of stimulation a higher levels of transcription were detected in response to the three serotypes over the non-infected condition (p < 0.0001); no evidence of statistically significant differences among serotypes was observed for 2 h and 24 h after infection (Figure 3B). The gene discussed is TLR4; the disease is infection.