HSP90B1 and cancer: Over the following years, reports have shown that cell surface GRP94 is highly expressed in various human cancer cell lines, such as SLR21 renal cancer, PANC10.05 pancreatic cancer, OVCAR3 ovarian cancer, DU-145 prostate cancer, WM1158 melanoma, and HCT-116 colorectal cancer cells [110,158,159].