IFN-γ has been shown to enhance tumor antigen presentation on MHC class I [119], reduce angiogenesis [120], induce production of IgG from B cells [121,122], activate macrophages and NK cells [123,124], promote Th1 differentiation [125] and have antiproliferative [126] and apoptotic effects [127]. Here, IFNG is linked to neoplasm.