It was reported that ATM mediated the Akt/GSK-3β/Snail signaling pathway in ovarian cancer cells (A2780, Hey, HeyA8, SKOV3, SKOV3ip1, OVCA433 and OVCA429 cell lines), xenograft mouse models of ovarian cancer and high grade serous ovarian cancer patients [57,58]. The gene discussed is AKT1; the disease is ovarian carcinoma.