TRPA1 and Alzheimer disease: An additional study revealed that in a different murine model of AD induced by 2,4-dinitrochlorobenzene (DNCB), genetic deletion of TRPA1 attenuated pathological findings of AD, including ear thickness, epidermal hyperplasia and pruritus, and dermal infiltration by mast cells, Th2 cytokines, and macrophages [96].