Ataxin-2 (ATXN2) is a protein conserved across eukaryotic organisms, that in humans is a genetic determinant of at least two neurodegenerative diseases, spinocerebellar ataxia type II (SCA2) and the amyotrophic lateral sclerosis (ALS) [6,7]. This evidence concerns the gene ATXN2 and spinocerebellar ataxia type 2.