CD40LG and autoimmune polyendocrinopathy: The aPL detection tests included in APS classification criteria described later are anticardiolipin (aCL) antibody (IgG or IgM) enzyme-linked immunosorbent assay (ELISA), anti-β2-GPI antibody (IgG or IgM) ELISA and lupus anticoagulant (LA) assay [2].