All six proteins are differentially expressed in malignant vs. healthy tissue in CRC (FBLN1 [45,46], MMP3 [47,48,49], ACTN4 [50,51], THBS1 [52], EDIL3 [53]) or other tumour entities (QSOX1 [54,55]). The gene discussed is ACTN4; the disease is colorectal carcinoma.