Due to the mutations of KRAS and EGFR in NSCLC are mutually exclusive, we divided our LUAD patients into WT and MT EGFR subgroups and found that the T allele of rs8193036 was only correlated with an advanced stage and lymph node metastasis in LUAD patients harboring the WT EGFR. Here, EGFR is linked to metastatic malignant neoplasm in the lymph nodes.