The incomplete EMT process in cancer cells is accompanied by the activation of EMT-transcription factors (EMT-TFs): TWIST, ZEB1-2, SLUG [3], which participate in increased cancer cell motility, allow dissemination of individual tumor cells or collective migration of cell clusters [3], but also have pleiotropic roles, that are not exclusively required for EMT [5]. This evidence concerns the gene TWIST1 and cancer.