This SNP is located on chromosome 10, and mutations in PDE6C have been linked to cone dystrophy type 4 (CODA) and achromatopsia, conditions that result from a loss of cone function characterized by low visual acuity, a lack of color discrimination, and excessive sensitivity to light with a sensation of discomfort or pain in the eyes [69]. This evidence concerns the gene PDE6C and familial cavitary optic disk anomaly.