The used search terms were ‘inflammatory bowel disease’, ‘tumor necrosis factor’, ‘Crohn’, ‘ulcerative colitis’, ‘TNF’, ‘adalimumab’, ‘certolizumab’, ‘infliximab’, ‘natalizumab’, ‘ustekinumab’, and ‘vedolizumab’. The gene discussed is TNF; the disease is inflammatory bowel disease.