CDKN2A and neoplasm: Over-expressed miR-30b, miR-32, miR-483-3p, miR-584, and miR-885-3p target tumor-suppressor genes such as CDKN2A, RB1, and NF2. The overexpression of miR-29c has been reported to behave as a tumor suppressor and mediates epigenetic effects, leading to downregulation of DNMT1 and DNMT3A genes [116].