ESR1 and neoplasm: In a multivariate analysis adjusted to tumor size and grade, presence of regional lymph node metastasis, and estrogen receptor status, the rs17102977 in CYP4X1 significantly associated with DFS in the unselected set of patients (p = 0.048; hazard ratio, HR = 1.69; 95% confidence interval, CI = 1.01–2.85).