Gene expression profiling of quadricep skeletal muscle biopsies from DMD patients and unaffected control patients were examined [40] and revealed a significant (p < 0.0001, n = 11; NCBI GEO profile GDS610 record) reduction in Mlip expression in the DMD affected patients while lamin A/C remained unaffected, suggesting that Mlip protein levels do not affect lamin A/C level of expression, whereas, shRNA mediated down-regulation of lamin A/C expression results in the up-regulation and cellular mislocalization of Mlip [5]. This evidence concerns the gene MLIP and Duchenne muscular dystrophy.